电话:010-83573219
X主要从事妊娠期高血压疾病的围产期保健和发病机制探讨,妊娠合并慢性肾脏疾病的围产期保健,感染性疾病对不良妊娠结局的影响等相关研究。具备丰富的临床经验,主持或参与多次产科危急重症抢救。现阶段在timi天美传孟若羽宁夏妇女儿童医院挂职(至2024年8月结束)。主持国家自然科学基金2项。
主要进行的临床研究包括妊娠合并慢性肾脏疾病的围产期保健,现已建立妊娠合并慢性肾病临床队列;妊娠期感染性疾病对妊娠结局的影响;子痫前期临床处理及发病机制研究,目前已建立复发性子痫前期临床研究队列,以及子痫前期潜在动物模型。
产科,围产保健,高危妊娠,妊娠期高血压疾病发病机制
1.&苍产蝉辫;国家自然科学基金(青年基金),项目批准号:81601303(已结题)
项目名称:补体旁路途径抑制因子贬因子在子痫前期发病机制中的作用
资助金额:17.5万元;执行年限:2017年1月-2019年12月
2.&苍产蝉辫;国家自然科学基金(面上项目),项目批准号:82071668(在研)
项目名称:痴贰骋贵通过磷酸化惭础厂笔1调节补体系统活化在贬贰尝尝笔综合征发病中的机制研究
资助金额:55万元;执行年限:2021年1月-2024年12月
3.&苍产蝉辫;中央高水平医院临床科研业务费资助(timi天美传孟若羽院内交叉临床研究)项目名称:子宫动脉血流联合补体系统活化因子表达水平对妊娠合并慢性肾病人群子痫前期的预测价值
资助金额:20万元;执行年限:2022年5月-2024年5月
1. Yingdong He, Jing Liu, Qingqing Cai, Jicheng Lv, Feng Yu, Qian Chen, Minghui Zhao. The pregnancy outcomes in patients with stage 3–4 chronic kidney disease and the effects of pregnancy in the long-term kidney function. J Nephrol. 2018. 31(6):953-960.
2. Yingdong He, Bingning Xu (co-first author), Di Song, Feng Yu, Qian Chen, Minghui Zhao. Normal range of complement components during pregnancy: a prospective study. Am J Reprod Immunol. 2020.2;83(2): e13202.
3. Yingdong He, Bingning Xu (co-first author), Menglu Wang, Yaqin Wang, Feng Yu, Qian Chen, Ming-hui Zhao. Dysregulation of complement system during pregnancy in patients with preeclampsia: a prospective study. Molecular Immunology. 2020.4;16(122):69-79.
4. Menglu Wang, Shi Chen (co-first author), Yingdong He, Minghui Zhao, Huixia Yang, Qian Chen. Low-dose aspirin for the prevention of severe preeclampsia in patients with chronic kidney disease: a retrospective study. J Nephrol.2021.10; 34(5):1631-1639.
5. Shi Chen, Zheng Li (co-first author), Yingdong He, Qian Chen. Dysregulation of complement system in HELLP syndrome. Hypertension in Pregnancy.2021.11;40 (4):303-311.
6. Yingdong He, Zheng Li (co-first author), Shi Chen, Jicheng Lv, Minghui Zhao, Qian Chen. Pregnancy in patients with stage 3–5 CKD: Maternal and fetal outcomes. Pregnancy Hypertension.2022.8;29:86-91.
7. Peizhi Deng, Qingwei Yu, Haibo Tang, Yao Lu, Yingdong He. Age at Menarche Mediating Visceral Adipose Tissue's Influence on Pre-eclampsia: A Mendelian Randomization Study. J Clin Endocrinol Metab. 2023.108(2):405-413. doi:10. 1210/clinem/dgac566.
8. Zheng Li, Shi Chen, Ying Tan, Jicheng Lv, Minghui Zhao, Qian Chen, Yingdong He. Twenty-four-hour proteinuria levels are associated with adverse pregnancy outcomes among women with CKD. Clinical Kidney Journal. 2023.1-10. https:/doi.org/10.1093/ckj/sfad044.
9. Ma Rui, Huang Liping, Wang Yanmin, Zhao Tingting, Chen Shi, He Yingdong. Regional differences in clinical characteristics and fetal and maternal outcomes of hypertensive disorders in pregnancy in China: a retrospective study. Hypertension in Pregnancy.2023. 42:1, 2234490.
性别:男
职称:副教授 、 主任医师
导师类别:博士研究生导师
所属院系:北京大学第一临床医学院
所属专业: 妇产科学
邮箱 : Dongyinghe1234@163.com
工作电话 : 010-83573219
产科,围产保健,高危妊娠,妊娠期高血压疾病发病机制