timi天美传孟若羽

团队介绍：

神经内科神经免疫疾病专业为神经内科主要学术团队之一。以高枫教授为团队负责人，拥有全国首个专职技术人员的神经免疫实验室。从神经免疫性疾病的诊治、多学科交叉形成了较为系统的疾病诊治及基础结合临床研究特色。本专业主持或参与多项国家级课题。发表多篇蝉肠颈文章及中文期刊文章。在国内同专业属于名列前茅。

项目情况：

视神经脊髓炎谱系疾病肠道微生物组学研究

多发性硬化肠道微生物组学研究

疾病修饰治疗对于多发性硬化的有效性和安全性研究

炎性脱髓鞘疾病患者炎性标志物研究

小鼠贰础贰模型机制研究

招生信息（拟招生的研究方向）：

炎性脱髓鞘病机制研究

科研项目：

timi天美传孟若羽交叉研究专项：长效醋酸格拉替雷对贰础贰模型的作用和机制研究

代表性研究成果：

Ran Liu, Shenglong Cao, Ya Hua, Richard F Keep, Yining Huang, Guohua Xi. CD163 expression in neurons after experimental intracerebral hemorrhage. Stroke 2017;48(5): 1369-1375.  

Wei Cui#, Ran Liu#, Haiqiang Jin, Pu Lv, Yuyao Sun, Xi Men, Saina Yang, Xiaozhong Qu, Zhenzhong Yang, Yining Huang*. pH gradient difference around ischemic brain tissue can serve as a trigger for delivering polyethyleneglycol-conjugated urokinase nanogels, Journal of Controlled Release, 2016;225:53-63.

Ran Liu, Haijiao Li, Ya Hua, Richard F.Keep, Jiangxi Xiao, Guohua Xi, Yining Huang. Early hemolysis within human intracerebral hematomas: an MRI study. Translational Stroke Research 2019; 10(1):52-56. 

Ran Liu, Haoran Zhang, Shuangjuan Cheng, Yuyao Sun, Haijiao Li, Jiangxi Xiao and Yining Huang. Association of brain iron overload with brain edema and brain atrophy after intracerebral hemorrhage. Frontiers in Neurology. 2020; 11:602413.  

Wei Cui#, Ran Liu*, Haiqiang Jin, Yining Huang, Wenhong Liu, Maolin He*. The protective effect of polyethylene glycol-conjugated urokinase nanogels in rat models of ischemic stroke when administrated outside the usual time window, Biochem Biophys Res Commun. 2020; 523(4):887-893.