timi天美传孟若羽

团队介绍：

本团队由研究员、助理研究员、博士后及研究生组成，主要研究方向为心血管疾病与痴呆的共防共治，主要基于自建的BRAVE队列以及国际知名队列数据库（如UKB、HRS、ELSA、CHARLS等）开展相关研究工作，近五年团队在JACC、Science Bulletin、JAMA Network Open等期刊发表SCI论文40余篇，其中ESI高被引论文2篇，团队负责人解武祥博士入选斯坦福大学发布的2023年度全球前2%顶尖科学家榜单。

项目情况：

代表性项目

(1) 2024.01-2026.12: 基于眼底照片的人工智能工具用于早期识别缺血性心脑血管疾病高风险人群的应用研究. 首都卫生发展科研专项项目. 主持 

(2) 2020.01-2023.12: 动脉硬化与阿尔兹海默病的关联及其表观遗传机制研究. 国家自然科学基金面上项目. 主持.

(3) 2020.01-2022.12: Association between retinal microvascular abnormalities and incident mild cognitive impairment and dementia. 2019年度米尔斯坦老年研究专项基金, 美国米尔斯坦亚美医学基金会. 主持. 

(4) 2016.03-2018.02: Dose-response relationship between air pollution and cardiovascular disease in Beijing. 2015年度牛顿国际学者项目, 英国医学科学会. 主持.

(5) 2014.01-2016.12: 前蛋白转化酶枯草溶菌素9与颈动脉粥样硬化进展关系的研究. 国家自然科学基金青年项目. 主持.

招生信息（拟招生的研究方向）：

临床研究方法学

科研项目：

目前在研项目包括美国中华医学会公开竞争项目（颁惭叠-翱2）、首都卫生发展科研专项项目等

代表性研究成果：

(1) Chenglong Li, Yidan Zhu, Yanjun Ma, Rong Hua, Baoliang Zhong, Wuxiang Xie (Correspondence). Association of Cumulative Blood Pressure with Cognitive Decline, Dementia and Mortality. Journal of the American College of Cardiology 2022;79(14):1321-1335 (ESI高被引论文).

(2) Wuxiang Xie (Correspondence and co-first)*, Fanfan Zheng*, Li Yan, Baoliang Zhong. Cognitive decline before and after coronary events. Journal of the American College of Cardiology 2019;73:3041-3050.

(3) Rong Hua, Yanjun Ma, Chenglong Li, Baoliang Zhong, Wuxiang Xie (Correspondence). Low levels of low-density lipoprotein cholesterol and cognitive decline. Science Bulletin 2021;66:1684-1690.

(4) Yanjun Ma, Jianhao Xiong, Yidan Zhu, Zongyuan Ge, Rong Hua, Meng Fu, Chenglong Li, Bin Wang, Li Dong, Xin Zhao, Jili Chen, Ce Rong, Chao He, Yuzhong Chen, Zhaohui Wang, Wenbin Wei, Wuxiang Xie (Co-correspondence)#, Yangfeng Wu#. Deep learning algorithm using fundus photographs for 10-year risk assessment of ischemic cardiovascular diseases in China. Science Bulletin 2021;67(1):17-20.

(5) Rong Hua, Jianhao Xiong, Gail Li, Yidan Zhu, Zongyuan Ge, Yanjun Ma, Meng Fu, Chenglong Li, Bin Wang, Li Dong, Xin Zhao, Zhiqiang Ma, Jili Chen, Xinxiao Gao, Chao He, Zhaohui Wang, Wenbin Wei, Fei Wang, Xiangyang Gao, Yuzhong Chen, Qiang Zeng, Wuxiang Xie (Co-correspondence). Development and validation of a deep learning algorithm based on fundus photographs for estimating the CAIDE dementia risk score. Age and Ageing 2022;51(12):afac282.

(6) Yanjun Ma, Lirong Liang, Fanfan Zheng, Le Shi, Baoliang Zhong, Wuxiang Xie (Correspondence). Association between sleep duration and cognitive decline: a pooled study of two nationally representative ageing cohorts. JAMA Network Open 2020;3(9):e2013573 (ESI高被引论文).

(7) Chenglong Li, Yanjun Ma, Chao Yang, Rong Hua, Wuxiang Xie (Co-correspondence)#, Luxia Zhang#. Association of cystatin-c kidney function metrics with long-term deficit accumulation frailty trajectories and physical function decline. JAMA Network Open 2022.

(8) Wenya Zhang, Jie Liang, Chenglong Li, Darui Gao, Qian Ma, Yang Pan, Yongqian Wang, Wuxiang Xie (Co-correspondence), Fanfan Zheng. Age at Diagnosis of Atrial Fibrillation and Incident Dementia. JAMA Network Open 2023;6(11):e2342744.

(9) Fanfan Zheng, Jie Liang, Chenglong Li, Qian Ma, Yang Pan, Wenya Zhang, Darui Gao, Yongqian Wang, Wuxiang Xie (Co-correspondence). Age at Onset of Heart Failure and Subsequent Risk of Dementia: A Longitudinal Cohort Study. JACC Heart Failure. Sep 27, 2023. Epublished DOI:10.1016/j.jchf.2023.08.006.

(10) Yanjun Ma, Rong Hua, Zhenchun Yang, Baoliang Zhong, Li Yan#, Wuxiang Xie (Co-correspondence) #. Different hypertension thresholds and cognitive decline: a pooled analysis of three aging cohorts. BMC Medicine 2021;19:287.