timi天美传孟若羽

团队介绍：

目前有在读博士1人、在读硕士2人、科研助理1人。

项目情况：

项目组主要研究方向为围术期脑保护及大数据分析。项目组主要围绕围术期脑损伤的主要并发症如谵妄、认知功能障碍和睡眠障碍开展临床研究，重点关注术前高危因素识别、术中精准化管理、药物预防和术后多模式镇痛等方面，以期建立降低围术期脑损伤的循证医学证据。项目组以鲍碍&苍产蝉辫;产颈辞产补苍办数据库为切入点，开展多项大数据分析研究，同时也建立一项纳入3000例受试者的队列人群，并仍在扩增样本量。

招生信息（拟招生的研究方向）：

麻醉学、生物信息学、流行病学

科研项目：

项目组目前承担国家重点研发计划子课题2项，中央高水平医院临床科研业务费资助课题1项以及横向课题3项，在研经费约260万元。

代表性研究成果：

1. Jia-Hui Ma, Ning-Hao Huang, Tao Huang*, Dong-Liang Mu*. 25-hydroxyvitamin D concentrations and risk of incident dementia, mild cognitive impairment, and delirium in 443,427 UK Biobank participants. Psychiatry Research. 2023(327):115369. https://doi.org/10.1016/j.psychres.2023.115369.

2. Guojun Wang, Shuting He, Mengyao Yu, Yan Zhang, Dongliang Mu*, Dongxin Wang. Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: a secondary analysis of a prospective observational study. Chin Med J (Engl). 2023 Mar 21. doi: 10.1097/CM9.0000000000002375. Online ahead of print.

3. Wenliang Su, Jiahang Ju, Minghui Gu, Xinrui Wang, Shaozhuang Liu, Jiawen Yu, Dongliang Mu*. SARS-CoV-2 envelope protein triggers depression-like behaviors and dysosmia via TLR2-mediated neuroinflammation in mice. J Neuroinflammation.2023 May 8;20(1):110. doi:10.1186/s12974-023-02786-x.

4. Xing MW, Li CJ, Guo C, Wang BJ, Mu DL*, Wang DX. Effect of intraoperative dexmedetomidine on long-term survival in older patients after major noncardiac surgery: 3-year follow-up of a randomized trial. J Clin Anesth. 2023 Jun;86:111068. doi: 10.1016/j.jclinane.2023.111068.

5. Jia-Hui Ma, Ya-Fei Liu, Hong Hong, Chun-Jing Li, Fan Cui, Dong-Liang Mu*, Dong-Xin Wang. Effect of acute pain on the association between preoperative cognitive impairment and postoperative delirium: a secondary analysis of three trials. Br J Anaesth. 2023 Feb; 130(2):e272-e280. doi: 10.1016/j.bja.2022.06.033. doi: